Optimization and characterization of primaquine-loaded solid lipid nanoparticles (SLN) for liver schinonticide targeting by freeze drying
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منابع مشابه
Optimization and Characterization of Primaquine-Loaded Solid Lipid Nanoparticles (SLN) for Liver Schinonticide Targeting by Freeze Drying
Submit Manuscript | http://medcraveonline.com Abbreviations: SLN: Solid Lipid Nanoparticles; PQ-SLNs: PQLoaded Solid Lipid Nanoparticles; o/w: Oil-in-Water; SA: Stearic Acid; PVA: Polyvinyl Alcohol; EtOAc: Ethyl Acetate; w/o: Waterin-Oil; PDI: Poly Dispersity Index; DLS: Dynamic Light Scattering; FD: Freeze Drying; HEPES: N-2-Hydroxyethylpiperazine-N-2Ethanesulfonic Acid; NP: Nanoformulated Pri...
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Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- and gastrointestinal-related side effects. Nanoformulation of drugs in an appropriate drug carrier system has been extensively studied and shown to have the potential to i...
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Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs. Proteins and antigens intended for therapeutic purpo...
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ژورنال
عنوان ژورنال: MOJ Drug Design Development & Therapy
سال: 2017
ISSN: 2575-9094
DOI: 10.15406/mojddt.2017.01.00021